In parallel with the redevelopment of the St Mary’s Hospital site, we are helping to bring together industry, academia, the NHS and local communities for the creation a new clinical life sciences cluster in Paddington, driving improved health, wealth and wellbeing.

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St Mary’s Hospital has been a leading provider of clinical care, education and research for over 175 years. The new St Mary’s will provide the clinical facilities we need to take us into the future as one of the most advanced, research-led, major trauma and acute hospitals in the world. Our plans, forming part of the government’s new hospitals programme, are for an 840 bed, state-of-the art facility including dedicated spaces for research, education and innovation.


Spanning three million square feet alongside the Grand Union Canal in Paddington, the redeveloped St Mary’s site will create a new kind of healthcare and life sciences complex. Alongside the hospital will be up to an additional 1.5 million square feet of cross-functional commercial and lab space for life sciences businesses to start, develop or grow.

Three female members of Trust staff

Alongside co-locating the hospital with more commercial and academic teams, within new specialist life sciences facilities, Paddington Life Sciences will enable us to bring new diagnostics and treatments to patients faster as well as give more people the chance to get involved in clinical trials for local, national, and global benefit.

With the new St Mary’s at its heart Paddington Life Sciences will put people first, bringing clinicians, researchers and our diverse north west London population of 2.4 million people together to create a critical mass of life sciences discovery and application on a scale not yet seen in the NHS. It will build on the global impact of our established life sciences track record, with the NIHR Imperial Biomedical Research Centre, a collaboration with Imperial College London, as the engine room, and enhanced by our commercial partnerships. And through co-location it will create connections that count across multiple clinical, academic and industry disciplines. 

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Research and innovation are fundamental to the clinical excellence for which our hospitals are renowned. We are now entering a new era of discovery, at an even more ambitious scale, by maximising the potential of our existing work areas and joining them up with new opportunities. Our wide ranging partnerships are intended to improve not just healthcare but also health and wellbeing, creating synergies that will boost local education, skills development and employment opportunities.
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Professor Tim Orchard, Chief executive, Imperial College Healthcare NHS Trust



Making the most of the clinical specialities and strengths of St Mary’s as well as the wider Imperial College Healthcare NHS Trust, we are focusing on expanding:

Canal at Imperial Wharf


Within this emerging life sciences cluster, three major initiatives are already underway: the Digital Collaboration Space, the Centre for Clinical Infection and Paddington Life Sciences Partners.


A new digital collaboration space has opened to boost health data-enabled research. It houses the NIHR Imperial BRC digital health programme team who will also use the space to encourage and host research collaborations between clinicians, academics, data scientists and partners from industry and local communities. 

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Bringing together NHS, academic, local authority and life sciences industry partners with a commitment to the area to help ensure the delivery of major social, health and commercial value as quickly as possible.

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The creation of a new centre for clinical infection, a specialist clinical and translational research facility to complement Imperial College London’s new Institute of Infection in South Kensington. Together they will be one of only a few resources in the world to offer ‘end-to-end’ innovation, from initial discovery to improved patient outcomes, for the management of infectious diseases as well as antimicrobial resistance.

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Find out more about our vision for Paddington Life Sciences