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Debbie Bourke, secretary
Dr Sayan Sen leads the Imperial College Healthcare NHS Trust cardiology service for central and west London. The service has been developed to accommodate all cardiac conditions, with tertiary centre cardiologists providing sub-speciality expertise in interventional cardiology, electrophysiology, heart failure and imaging. Dr Sen is an interventional cardiologist at Hammersmith Hospital and is part of the primary angioplasty service. He routinely performs complex coronary angioplasty, pacemaker insertion and transcatheter aortic valve implantation (TAVI). He is recognised as an international expert in this field and is often invited to perform these procedures in hospitals around the world or as a 'live' case operator to international conferences.
Dr Sen studied medicine at University College London (UCL), achieving a first class (honours) BSc degree in medical sciences and neuroscience in 2000. He graduated with distinction in his final MBBS examinations in 2003. Dr Sen's academic awards include the Royal Society of Medicine Investigator of the Year Award (All Sections, 2013), the Royal Society of Medicine President's Gold Medal (cardiology section, 2013), the prestigious Imperial College Armstrong Medal and Prize (2012), the Young Investigator Award at the British Cardiac Intervention Society Advanced Coronary Intervention meeting (2012), and the Young Investigator Prize at the Translating Coronary Physiology and Biophysics to Clinical Applications Symposium, Amsterdam (2010). He was shortlisted as a Young Investigator finalist at the British Hypertension Society and Artery meetings (2010).
Chest pain, palpitations, shortness of breath, dizziness and blackouts, hypertension, hypersholesterolaemia, coronary artery disease, heart attacks (STEMI, NSTEMI), valvular heart disease, severe aortic stenosis - TAVI, pacemakers
Research & publications
Dr Sen's academic interests are dedicated to improving patient care. They include the development and validation of new diagnostic tools, determining how study design can influence the clinical use of competing therapies and the development and application of tools that permit a more patient-centred approach to therapy. His research has been published in leading cardiology journals and has changed clinical practice around the world. In 2009, he was awarded the prestigious Medical Research Council (MRC) Clinical Research Training Fellowship to study the haemodynamic changes in coronary artery bypass grafts, diseased coronary arteries and the haemodynamic changes associated with percutaneous aortic valve insertion. His work involves close collaboration with the bioengineering department at Imperial College London and the MRC Clinical Sciences Centre. One of the themes of his research is to determine which patients should be treated with stents. Dr Sen's PhD introduced and developed a new technique of stenosis evaluation (the instantaneous wave-free ratio, iFR). This index has been globally adopted by physicians to help guide how they treat patients with coronary artery disease. He is the first author of the ADVISE and CLARIFY studies that demonstrate the potential of iFR and have challenged the current concepts of coronary physiology. Currently, in addition to being the principal investigator of several first-in-man physiological studies, he is also the medical director of the FLAIR trial - a global multi-centre randomised study comparing iFR to existing techniques.