Dr Patrick Mallia qualified in Malta and came to the UK to pursue specialty medical training. After clinical jobs in Edinburgh and Stoke-on-Trent, he moved to London where he completed a PhD at Imperial College London and completed his training in respiratory medicine and general medicine.
Chronic pulmonary obstructive disease (COPD), asthma
Research & publications
Dr Mallia's research interests are the role of respiratory viruses and bacterial infection in COPD and asthma exacerbations.
Finney L, Berry M, Singanayagam A, Elkin SL, Johnston SL, Mallia P. (2014) Inhaled corticosteroids and pneumonia in chronic obstructive pulmonary disease. Lancet Respir Med, Nov;2(11):919–32
Footitt J, Mallia P, Durham AL, Ho WE, Trujillo-Torralbo MB, Telcian AG, Del Rosario A, Chang C, Peh HY, Kebadze T, Aniscenko J, Stanciu L, Essilfie-Quaye S, Ito K, Barnes PJ, Elkin SL, Kon OM, Wong WS, Adcock IM, Johnston SL. (2016) Oxidative and nitrosative stress and histone deacetylase-2 activity in exacerbations of COPD. Chest, Jan;149(1):62–73
Hewitt R, Farne H, Ritchie A, Luke E, Johnston SL, Mallia P. (2016) The role of viral infections in exacerbations of chronic obstructive pulmonary disease and asthma. Ther Adv Respir Dis, Apr;10(2):158–74
Johnston SL, Szigeti M, Cross M, Brightling C, Chaudhuri R, Harrison T, Mansur A, Robison L, Sattar Z, Jackson D, Mallia P, Wong E, Corrigan C, Higgins B, Ind P, Singh D, Thomson NC, Ashby D, Chauhan A; AZALEA Trial Team (2016) Azithromycin for acute exacerbations of asthma: the AZALEA randomized clinical trial. JAMA Intern Med,16 Nov 1;176(11):1630–37
Mallia P, Footitt J, Sotero R, Jepson A, Contoli M, Trujillo-Torralbo MB, Kebadze T, Aniscenko J, Oleszkiewicz G, Gray K, Message SD, Ito K, Barnes PJ, Adcock IM, Papi A, Stanciu LA, Elkin SL, Kon OM, Johnson M, Johnston SL. (2012) Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. Dec 1;186(11):1117–24
Mallia P, Message SD, Gielen V, Contoli M, Gray K, Kebadze T, Aniscenko J, Laza-Stanca V, Edwards MR, Slater L, Papi A, Stanciu LA, Kon OM, Johnson M, Johnston SL. (2011) Experimental rhinovirus infection as a human model of chronic obstructive pulmonary disease exacerbation. Am J Respir Crit Care Med. 2011 Mar 15;183(6):734–42