Participation in dementia and memory loss clinical research is always voluntary; even if you decide to be involved you will be able to withdraw from the trial at any time. Withdrawing from a research study will not affect any on-going treatment you receive.

Clinical trials and research

We are a dedicated clinical trials facility and we run clinical trials for patients with memory and cognitive problems.

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Our aim is to provide our patients with the opportunity to benefit from the latest developments in research. This may involve new types of brain scan or the newest treatments for dementia. In contrast to currently available drugs therapy, many of these trials are aimed at developing drugs that affect the underlying processes in dementia.

Our clinical trials team is comprised of experienced and sympathetic doctors, nurses, and psychologists. All our trials have full ethical approval and are run in our comfortable and well-equipped unit where safety and a positive patient experience are paramount.

For all our studies, travel costs will be reimbursed and if necessary, transport to the unit can be arranged. Refreshments will be provided during your visit.

Recent studies include:

  • A clinical trial investigating the effects of a potential disease modifying treatment in mild to moderate Alzheimer’s disease
  • A clinical trial investigating cognitive enhancing therapy in moderate Alzheimer’s disease
  • A treatment trial of a new medication designed to reduce levels of brain amyloid and delay progression in patients with mild cognitive impairment

Patients can be referred by their GPs or specialists. We also welcome patients to refer themselves!

Participation in dementia and memory loss clinical research is always voluntary; even if you decide to be involved you will be able to withdraw from the trial at any time. Withdrawing from a research study will not affect any on-going treatment you receive.

What might research participation involve?
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  • attending the Imperial memory clinic throughout the study (you will be reimbursed for your transport to and from appointments)
  • investigations, such as blood samples, having an MRI or PET scan, and physical examinations
  • completing memory assessment tests
  • taking a tablet or receiving an injection
  • a family member may be asked to complete questionnaires.

Who can take part?
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A clinical trial needs to be right for the patient, and the patient needs to be right for the clinical trial. There are often very specific criteria that need to be met for someone to take part in a clinical trial. For memory clinical trials you normally need:

  • to have a memory problem or a diagnosis of dementia (some trials involve participants who are known to be at risk of developing dementia but do not have memory problems)
  • to live independently (rather than living in a residential or nursing home)
  • to be reasonably physically healthy
  • to be able to take the study medication your current medications
  • to be at a stable dose to complete our memory assessment test, and score at an appropriate level
  • to be willing and able to undertake procedures such as blood tests and brain scans
  • to have a family member or friend who can come to appointments with you.