Coronavirus update for sexual health services

We’re making changes to our sexual health and HIV services to help respond to coronavirus and protect our patients, staff and visitors. Learn more on our sexual health page.

About GUYS@Mary’s clinic

The GUYS@Mary’s clinic is a free, confidential sexual health service for men who have sex with men, which provides sexual health testing and treatment for men who are experiencing symptoms and advice on PEP and PrEP.

The GUYS@Mary’s clinic offers the following services:

  • Rapid HIV testing with results within five minutes

  • Testing and treatment of sexually transmitted infections

  • Post-exposure prophylaxis for HIV (PEP)

  • Pre-exposure prophylaxis (PrEP) support and advice

  • Hepatitis A and B vaccinations

  • Human papillomavirus (HPV) vaccinations

  • Safe sex advice

  • Chemsex advice and support

  • Free condoms

Appointments for PEP or PrEP advice, symptoms and treatment

If you wish to discuss PEP or PrEP, are experiencing symptoms, or need treatment, please book an appointment on 0203 312 1225.

Pre-Exposure Prophylaxis or PrEP

Pre-Exposure Prophylaxis (PrEP) is medication that people who are at very high risk of catching HIV, can take to prevent HIV and is now available on the NHS.

Depending on the type of sex you have and your medical history there are different ways that you can take PrEP, and it is extremely effective if taken correctly.

Not everyone can take PrEP, for example some medications can interact badly, and it won’t work if you are already HIV-positive.

It is important to remember however it will not protect you against the other sexually transmitted infections (STIs) such as gonorrhea or syphilis.

People who take PrEP are recommended to have 3-monthly checkups for STIs and regular tests to ensure your kidneys are working well.

If you would like to find out more about PrEP, discuss starting PrEP, or be monitored while taking PrEP, please call 0203 312 1225 to arrange to speak to one of the team.

We also recommend that you read the this PrEP leaflet on the  i-Base website

NHS PrEP trial

The PrEP trial (also known as the IMPACT trial) is closed to new participants. The final visit for the trial must be undertaken before 12th October, at that visit you will be switched over to NHS funded PrEP.
If you are already enrolled on the trial and either need an appointment or are running low on tablets, please book an appointment to arrange to speak to one of the team.

Men who are not experiencing symptoms and don’t need PEP or PrEP advice

Men who are not experiencing symptoms and don’t need PEP or PrEP advice can get an online sexual health check-up with Sexual Health London .  If you live in a borough where the Sexual Health London service is not available, you can find your local service either through SH24 or (NHS Choices).

If you need a sexual health check-up and vaccinations,  Please call 0203 312 1225

Contact details


GUYS@Mary's clinic
First floor
Jefferiss Wing
Praed Street
St Mary's Hospital
London W2 1NY


This clinic is run on Wednesdays from 17.00 to 19.10.


020 3312 1225

What to expect at your appointment

When you arrive please go to the clinic reception on the first floor of the Jefferiss Wing. If you are a new patient you will be asked to complete a short registration form.

You will receive some results during your visit and any others will be sent via a text message within a week.


Entry to the clinic is by self-referral through the online booking service above.